| Diva | OKDB#: 10 |
| Symbols: | Bcl2110 | Species: | mouse | ||
| Synonyms: | Death Inducer binding to Viral Bcl-2 and Apaf-1; Bcl-2 homologue of ovary; Boo | Locus: |
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R-L INTERACTIONS MGI |
| General Comment |
Diva (Death Inducer binding to Viral Bcl-2 and Apaf-1 ) is a Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell death (Inohara et al., 1998; Song et al., 1999). It is also known as BOO ( Bcl-2 homologue of ovary) but found to be an anti-apoptotic member of the Bcl-2 family. Boo is exclusively expressed in the ovary, the epididymis and embryos (brain, liver and heart) ,
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| General function | Cell death/survival, Apoptosis | |||
| Comment | ||||
| Cellular localization | Mitochondrial | |||
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| Ovarian function | Follicle atresia | |||
| Comment | ||||
| Expression regulated by | ||||
| Comment | ||||
| Ovarian localization | Oocyte, Granulosa | |||
| Comment | ||||
| Follicle stages | Antral | |||
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| Phenotypes | ||||
| Mutations | 0 mutations | |||
| Genomic Region | show genomic region | |||
| Phenotypes and GWAS | show phenotypes and GWAS | |||
| Links |
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| created: | March 10, 1999, midnight | by: |
Bae email:
home page: |
| last update: | Nov. 21, 2012, 12:16 p.m. | by: | hsueh email: |
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