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Hsueh lab

HPMR

p75(NTR)-associated cell death executor

OKDB#: 1248

	Symbols:	p75(NTR)-associated cell death executor		Species:	human
	Synonyms:	NADE\|		Locus:

For retrieval of Nucleotide and Amino Acid sequences please go to: OMIM UCSC Genome Browser GEO Profiles ^new! Amazonia (transcriptome data) ^new!
R-L INTERACTIONS MGI

General Comment

Using a yeast 2-hybrid screen with the cytosolic domain of p75(NTR) as bait, Mukai et al. (2000 obtained cDNAs encoding mouse and human p75(NTR)-associated cell death executor, or NADE. Human NADE is identical to the the HGR74 cDNA cloned by Rapp et al. (1990) from an ovarian granulosa cDNA library. HGR74 was expressed in testis, prostate, seminal vesicle, and ovarian granulosa cells.

General function

Cell death/survival, Apoptosis

Comment

Cellular localization

Comment

Ovarian function

Comment

Expression regulated by

Comment

Ovarian localization

Granulosa

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Follicle stages

Comment

Phenotypes

Mutations

0 mutations

Genomic Region

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Phenotypes and GWAS

show phenotypes and GWAS

Links

OMIM (Online Mendelian Inheritance in Man: an excellent source of general gene description and genetic information.)
OMIM \ Animal Model
KEGG Pathways

Recent Publications

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created:

July 31, 2001, 1:39 p.m.

by:

hsueh email:
home page:

last update:

Aug. 14, 2001, 10:41 a.m.

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