| POTASSIUM CHANNEL, SUBFAMILY K, MEMBER 9; KCNK9 | OKDB#: 1376 |
| Symbols: | POTASSIUM CHANNEL, SUBFAMILY K, MEMBER 9; KCNK9 | Species: | human | ||
| Synonyms: | TWIK-RELATED ACID-SENSITIVE K+ CHANNEL 3, TASK3| | Locus: | 8 in Homo sapiens |
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| General Comment |
Ashmole I, et al cloned a novel member of the tandem pore K+ channel family from
human brain cDNA. The novel cDNA encodes a 330-residue polypeptide of
predicted molecular mass 36 kDa. It was named the channel TASK-5 owing to
its sequence homology with TASK-1 and TASK-3. TASK-5 mRNA is expressed
in pancreas, liver, kidney, lung, ovary, testis and heart.
NCBI Summary: This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This open channel is highly expressed in the cerebellum. It is inhibited by extracellular acidification and arachidonic acid, and strongly inhibited by phorbol 12-myristate 13-acetate. |
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| General function | Channel/transport protein | ||||
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| Cellular localization | Plasma membrane | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | Nov. 25, 2001, 7:34 a.m. | by: |
hsueh email:
home page: |
| last update: | Nov. 25, 2001, 7:34 a.m. | by: | system email: |
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