| SOX33 | OKDB#: 2097 |
| Symbols: | SOX33 | Species: | xenopus l. | ||
| Synonyms: | Locus: |
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R-L INTERACTIONS MGI |
| General Comment |
Hagiuda J, et al reported a novel Xenopus laevis SRY-related gene, xSox33.
The sex-determining region Y (SRY) gene and its related Sox genes encode transcriptional
regulatory factors. In this study, the authors isolated and sequenced a novel Sox cDNA from African clawed
frog (Xenopus laevis). The Sox gene was named xSox33. xSox33 was revealed to encode 244
amino acids. Reverse transcription-polymerase chain reaction (RT-PCR) showed that xSox33 was
expressed at very low levels in some frog tissues including lung, ovary, skeletal muscle, testis,
brain and heart. Its embryonic expression was also studied by RT-PCR. After the mid-blastula
transition, the zygotic expression was initiated during gastrulation and the level was elevated as the
embryogenesis proceeded. Electrophoretic mobility shift assay (EMSA) indicated that a
recombinant xSox33 polypeptide was capable of binding to the nucleotide sequence AACAAT.
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| General function | DNA binding, Transcription factor | |||
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| Cellular localization | Nuclear | |||
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| Ovarian function | ||||
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| Expression regulated by | ||||
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| Ovarian localization | ||||
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| Follicle stages | ||||
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| Phenotypes | ||||
| Mutations | 0 mutations | |||
| Genomic Region | show genomic region | |||
| Phenotypes and GWAS | show phenotypes and GWAS | |||
| Links |
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| created: | Aug. 6, 2003, 5:21 p.m. | by: |
hsueh email:
home page: |
| last update: | Nov. 9, 2005, 12:19 p.m. | by: | system email: |
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