| Macrophage Mannose Receptor | OKDB#: 2197 |
| Symbols: | MRC1 | Species: | human | ||
| Synonyms: | Locus: | 10p13 in Homo sapiens | HPMR |
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| General Comment | NCBI Summary: The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. | ||||
| General function | Receptor | ||||
| Comment | |||||
| Cellular localization | Plasma membrane | ||||
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| Ovarian function | |||||
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| Expression regulated by | |||||
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| Ovarian localization | |||||
| Comment | This gene was found in a mouse DNA array analysis of transcripts expressed in mouse preovulatory follicles. | ||||
| Follicle stages | |||||
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| Phenotypes | |||||
| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
| Links |
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| created: | Oct. 14, 2003, 12:10 p.m. | by: |
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| last update: | March 28, 2004, 4:12 p.m. | by: | system email: |
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