| Integrin, Alpha-2 | OKDB#: 2257 |
| Symbols: | ITGA2 | Species: | human | ||
| Synonyms: | VERY LATE ACTIVATION PROTEIN 2 RECEPTOR, ALPHA-2 SUBUNIT|VLA2 RECEPTOR, ALPHA-2 SUBUNIT, VLAA2|CD49B|PLATELET GLYCOPROTEIN Ia/IIa|PLATELET RECEPTOR FOR COLLAGEN, DEFICIENCY OF, INCLUDED|GLYCOPROTEIN Ia DEFICIENCY, INCLUDED|GP Ia DEFICIENCY, INCLUDED|PLATE | Locus: | 5q23-q31 in Homo sapiens | HPMR |
|
For retrieval of Nucleotide and Amino Acid sequences please go to:
OMIM
Entrez Gene
Mammalian Reproductive Genetics Endometrium Database Resource Orthologous Genes UCSC Genome Browser GEO Profiles new! Amazonia (transcriptome data) new! R-L INTERACTIONS MGI |
| General Comment |
This gene was found through a mouse ovarian follicle microarray.
NCBI Summary: ITGA2 encodes integrin alpha chain 2. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing alpha integrin 2 combines with beta integrin 1 to form a collagen-binding integrin referred to as glycoprotein Ia/IIa when expressed on on platelets, and very late (activation) antigen 2 ('VLA-2') when found on T-cells. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. |
||||
| General function | Receptor | ||||
| Comment | |||||
| Cellular localization | Plasma membrane | ||||
| Comment | |||||
| Ovarian function | |||||
| Comment | |||||
| Expression regulated by | |||||
| Comment | |||||
| Ovarian localization | |||||
| Comment | |||||
| Follicle stages | |||||
| Comment | |||||
| Phenotypes | |||||
| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
| Links |
|
| created: | Nov. 10, 2003, 11:47 a.m. | by: |
xin email:
home page: |
| last update: | Nov. 15, 2003, 4:15 p.m. | by: | system email: |
Click here to return to gene search form