| Opioid Growth Factor Receptor | OKDB#: 2269 |
| Symbols: | OGFR | Species: | human | ||
| Synonyms: | MAC2-BINDING PROTEIN, MAC2BP| SERUM PROTEIN 90K, 90K| L3 ANTIGEN| | Locus: | 17q25 in Homo sapiens | HPMR |
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| General Comment |
This gene was found through a mouse ovarian follicle microarray.
NCBI Summary: The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. |
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| General function | Receptor | ||||
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| Cellular localization | Plasma membrane | ||||
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| Ovarian function | |||||
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| Ovarian localization | |||||
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| Follicle stages | |||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
| Links |
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| created: | Nov. 10, 2003, 12:25 p.m. | by: |
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| last update: | Nov. 15, 2003, 4:20 p.m. | by: | system email: |
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