| metallothionein 2A | OKDB#: 2311 |
| Symbols: | metallothionein 2A | Species: | human | ||
| Synonyms: | Locus: |
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R-L INTERACTIONS MGI |
| General Comment |
metallothioneins (MTs) as a family of low molecular weight, heavy metal-binding proteins characterized by a high cysteine content and lack of aromatic amino acids. MTs bind 7 to 12 heavy metal atoms per molecule of protein. They are ubiquitous in the animal and plant kingdoms and are found in prokaryotes. In mammals, the cysteine residues are absolutely conserved and serve to coordinate heavy metal atoms such as zinc, cadmium, and copper via mercaptide linkages
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| General function | ||||
| Comment | ||||
| Cellular localization | Cytoplasmic | |||
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| Ovarian function | ||||
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| Expression regulated by | FSH | |||
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| Ovarian localization | Granulosa | |||
| Comment | Sasson et al 2003 reported Novel genes modulated by FSH in normal and immortalized FSH-responsive cells: new insights into the mechanism of FSH action. This gene is up-regulated by FSH. | |||
| Follicle stages | ||||
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| Phenotypes | ||||
| Mutations | 0 mutations | |||
| Genomic Region | show genomic region | |||
| Phenotypes and GWAS | show phenotypes and GWAS | |||
| Links |
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| created: | Dec. 13, 2003, 5:25 p.m. | by: |
hsueh email:
home page: |
| last update: | Dec. 13, 2003, 5:25 p.m. | by: | system email: |
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