| Caspase 13 | OKDB#: 2355 |
| Symbols: | Caspase 13 | Species: | cow | ||
| Synonyms: | Locus: |
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R-L INTERACTIONS MGI |
| General Comment |
Deregulation of apoptosis is responsible for a wide range of diseases such as autoimmune and neurodegenerative disorders. By sequence homology searches using the catalytic domains of 2 serine/threonine kinases important in the regulation of apoptosis, DAP kinase (600954) and ZIP kinase (603289), Sanjo et al. (1998) cloned 2 novel members of the ser/thr protein kinase family, which they termed DRAK1 (604726) and DRAK2, but which were later designated STK17A and STK17B, respectively.
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| General function | Cell death/survival, Apoptosis | |||
| Comment | ||||
| Cellular localization | Cytoplasmic | |||
| Comment | ||||
| Ovarian function | Follicle atresia | |||
| Comment | ||||
| Expression regulated by | ||||
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| Ovarian localization | Granulosa, Theca | |||
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| Follicle stages | Antral, Preovulatory | |||
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| Phenotypes | ||||
| Mutations | 0 mutations | |||
| Genomic Region | show genomic region | |||
| Phenotypes and GWAS | show phenotypes and GWAS | |||
| Links |
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| created: | Jan. 28, 2004, 3:17 p.m. | by: |
hsueh email:
home page: |
| last update: | Jan. 28, 2004, 3:17 p.m. | by: | system email: |
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