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Ovarian Kaleidoscope Database (OKdb)

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Caspase 13 OKDB#: 2355
 Symbols: Caspase 13 Species: cow
 Synonyms:  Locus:


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General Comment Deregulation of apoptosis is responsible for a wide range of diseases such as autoimmune and neurodegenerative disorders. By sequence homology searches using the catalytic domains of 2 serine/threonine kinases important in the regulation of apoptosis, DAP kinase (600954) and ZIP kinase (603289), Sanjo et al. (1998) cloned 2 novel members of the ser/thr protein kinase family, which they termed DRAK1 (604726) and DRAK2, but which were later designated STK17A and STK17B, respectively.

General function Cell death/survival, Apoptosis
Comment
Cellular localization Cytoplasmic
Comment
Ovarian function Follicle atresia
Comment
Expression regulated by
Comment
Ovarian localization Granulosa, Theca
Comment
Follicle stages Antral, Preovulatory
Comment
Phenotypes
Mutations 0 mutations
Genomic Region show genomic region
Phenotypes and GWAS show phenotypes and GWAS
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created: Jan. 28, 2004, 3:17 p.m. by: hsueh   email:
home page:
last update: Jan. 28, 2004, 3:17 p.m. by: system    email:



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