| vascular endothelial growth factor D | OKDB#: 2482 |
| Symbols: | VEGFD | Species: | human | ||
| Synonyms: | FIGF, VEGF-D | Locus: | Xp22.2 in Homo sapiens |
|
For retrieval of Nucleotide and Amino Acid sequences please go to:
OMIM
Entrez Gene
Mammalian Reproductive Genetics Endometrium Database Resource Orthologous Genes UCSC Genome Browser GEO Profiles new! Amazonia (transcriptome data) new! R-L INTERACTIONS MGI |
| General Comment | NCBI Summary: The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011] | ||||
| General function | Ligand, Growth factor | ||||
| Comment | |||||
| Cellular localization | Secreted | ||||
| Comment | |||||
| Ovarian function | Luteinization | ||||
| Comment | |||||
| Expression regulated by | FSH, LH | ||||
| Comment | Major increases after LH | ||||
| Ovarian localization | Granulosa, Luteal cells | ||||
| Comment | |||||
| Follicle stages | Secondary | ||||
| Comment | |||||
| Phenotypes | |||||
| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
| Links |
|
| created: | May 24, 2004, 8:39 a.m. | by: |
vijay email:
home page: |
| last update: | May 7, 2021, 2:42 p.m. | by: | hsueh email: |
Click here to return to gene search form