| Alcohol Dehydrogenase 7 | OKDB#: 2683 |
| Symbols: | ADH7 | Species: | human | ||
| Synonyms: | ADH, CLASS IV | Locus: | 4q23-q24 in Homo sapiens |
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| General Comment |
Change in gene expression identified in DNA Microarray experiments. This gene is involved in fatty acid metabolism.
NCBI Summary: This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members. |
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| General function | Enzyme | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | Dec. 1, 2004, 2:56 p.m. | by: |
rami email:
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| last update: | Dec. 2, 2004, 2:28 p.m. | by: | system email: |
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