| Cutaneous T-cell Lymphoma-associated Antigen 1 | OKDB#: 2824 |
| Symbols: | CTAGE1 | Species: | human | ||
| Synonyms: | CUTANEOUS T-CELL LYMPHOMA-ASSOCIATED ANTIGEN 2, INCLUDED, CTAGE2, INCLUDED | Locus: |
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R-L INTERACTIONS MGI |
| General Comment | |||||
| General function | |||||
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| Cellular localization | Nuclear | ||||
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| Ovarian function | |||||
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| Expression regulated by | |||||
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| Ovarian localization | |||||
| Comment | Differentially expressed nucleolar TGF-beta1 target (DENTT) shows tissue-specific nuclear and cytoplasmic localization and increases TGF-beta1-responsive transcription in primates. Ozbun LL, et al . Differentially Expressed Nucleolar TGF-beta1 Target (DENTT) is a new member of the TSPY/TSPY-like/SET/NAP-1 (TTSN) superfamily whose mRNA is induced by TGF-beta1 in TGF-beta1-responsive human lung cancer cells. Monkey DENTT mRNA contains a 2085-bp open reading frame that encodes a predicted polypeptide of 695 amino acids with five nuclear localization signals, two coiled-coil regions, and a domain that shows significant identity to a region that defines the TTSN superfamily. RT-PCR amplification and Western blot analyses showed DENTT mRNA and protein in adult monkey tissues, including the adrenal gland, cerebral cortex, and ovary. | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
| Links |
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| created: | April 20, 2005, 3:42 p.m. | by: |
hsueh email:
home page: |
| last update: | April 20, 2005, 3:42 p.m. | by: | system email: |
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