| Wingless-type Mmtv Integration Site Family, Member 9a | OKDB#: 2975 |
| Symbols: | WNT9A | Species: | human | ||
| Synonyms: | WNT14,WINGLESS-TYPE MMTV INTEGRATION SITE FAMILY, MEMBER 14, WNT14 | Locus: | 1q42 in Homo sapiens |
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| General Comment |
Expression profiling of purified mouse gonadal somatic cells during the critical time window of sex determination reveals novel candidate genes for human sexual dysgenesis syndromes Beverdam A, et al.This gene was upregulated in 11.5 dpc female somatic gonad cells.
NCBI Summary: The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is expressed in gastric cancer cell lines. The protein encoded by this gene shows 75% amino acid identity to chicken Wnt14, which has been shown to play a central role in initiating synovial joint formation in the chick limb. This gene is clustered with another family member, WNT3A, in the chromosome 1q42 region. |
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| General function | Ligand | ||||
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| Cellular localization | Secreted | ||||
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| Ovarian localization | Primordial Germ Cell | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
| Links |
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| created: | Jan. 11, 2006, 11:20 a.m. | by: |
rami email:
home page: |
| last update: | Jan. 11, 2006, 12:03 p.m. | by: | hsueh email: |
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