| Transglutaminase 3 | OKDB#: 2991 |
| Symbols: | TGM3 | Species: | human | ||
| Synonyms: | TGE, MGC126249, MGC126250,TRANSGLUTAMINASE E, TGE | Locus: | 20q11.2 in Homo sapiens |
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Entrez Gene
Mammalian Reproductive Genetics Endometrium Database Resource Orthologous Genes UCSC Genome Browser GEO Profiles new! Amazonia (transcriptome data) new! R-L INTERACTIONS MGI |
| General Comment |
Expression profiling of purified mouse gonadal somatic cells during the critical time window of sex determination reveals novel candidate genes for human sexual dysgenesis syndromes Beverdam A, et al.This gene was upregulated in 11.5 dpc female somatic gonad cells.
NCBI Summary: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle. |
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| General function | Enzyme | ||||
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| Ovarian localization | Primordial Germ Cell | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | Jan. 11, 2006, 11:29 a.m. | by: |
rami email:
home page: |
| last update: | Jan. 11, 2006, 12:16 p.m. | by: | hsueh email: |
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