| Anaphase-promoting Complex, Subunit 1 | OKDB#: 3058 |
| Symbols: | ANAPC1 | Species: | human | ||
| Synonyms: | APC1, MCPR, TSG24,APC1 | Locus: | 2q12.1 in Homo sapiens |
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OMIM
Entrez Gene
Mammalian Reproductive Genetics Endometrium Database Resource Orthologous Genes UCSC Genome Browser GEO Profiles new! Amazonia (transcriptome data) new! R-L INTERACTIONS MGI |
| General Comment | NCBI Summary: ANAPC1 is 1 of at least 10 subunits of the anaphase-promoting complex (APC), which functions at the metaphase-to-anaphase transition of the cell cycle and is regulated by spindle checkpoint proteins. The APC is an E3 ubiquitin ligase that targets cell cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle.[supplied by OMIM] | ||||
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| Ovarian localization | Oocyte | ||||
| Comment | The human cumulus-oocyte complex gene-expression profile. Assou S et al. BACKGROUND: The understanding of the mechanisms regulating human oocyte maturation is still rudimentary. We have identified transcripts differentially expressed between immature and mature oocytes and cumulus cells. | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | April 26, 2006, 1:03 p.m. | by: |
rami email:
home page: |
| last update: | April 26, 2006, 1:03 p.m. | by: | rami email: |
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