| Peroxiredoxin 5 | OKDB#: 3108 |
| Symbols: | PRDX5 | Species: | human | ||
| Synonyms: | PLP, ACR1, B166, PRXV, PMP20, PRDX6, SBBI10, AOEB166, MGC117264,ANTIOXIDANT ENZYME B166, AOEB166 | Locus: | 11q13 in Homo sapiens |
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| General Comment | NCBI Summary: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. This gene uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms. Three transcript variants encoding distinct isoforms have been identified for this gene. | ||||
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| Ovarian localization | Cumulus | ||||
| Comment | The human cumulus-oocyte complex gene-expression profile. Assou S et al. BACKGROUND: The understanding of the mechanisms regulating human oocyte maturation is still rudimentary. We have identified transcripts differentially expressed between immature and mature oocytes and cumulus cells. | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | June 20, 2006, 11:27 a.m. | by: |
Alex email:
home page: |
| last update: | June 20, 2006, 11:27 a.m. | by: | Alex email: |
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