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Growth Arrest- And Dna Damage-inducible Gene Gadd45, Gamma OKDB#: 3133
 Symbols: GADD45G Species: human
 Synonyms: CR6, DDIT2, GRP17, GADD45gamma,GADD-RELATED PROTEIN, 17-KD, GRP17|OIG37, MOUSE, HOMOLOG OF  Locus: 9q22.1-q22.2 in Homo sapiens


For retrieval of Nucleotide and Amino Acid sequences please go to: OMIM Entrez Gene
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link to BioGPS
General Comment NCBI Summary: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.
General function Intracellular signaling cascade, Cell cycle regulation
Comment
Cellular localization Cytoplasmic
Comment
Ovarian function
Comment
Expression regulated by
Comment
Ovarian localization Oocyte
Comment
Follicle stages Primordial
Comment Arraztoa JA, et al 2005 reported the identification of genes expressed in primate primordial oocytes.
Phenotypes
Mutations 0 mutations
Genomic Region show genomic region
Phenotypes and GWAS show phenotypes and GWAS
Links
OMIM (Online Mendelian Inheritance in Man: an excellent source of general gene description and genetic information.)
OMIM \ Animal Model
KEGG Pathways
Recent Publications
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created: June 21, 2006, 10:26 a.m. by: alex   email:
home page:
last update: July 14, 2006, 4:36 p.m. by: hsueh    email:



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