| Growth Arrest- And Dna Damage-inducible Gene Gadd45, Gamma | OKDB#: 3133 |
| Symbols: | GADD45G | Species: | human | ||
| Synonyms: | CR6, DDIT2, GRP17, GADD45gamma,GADD-RELATED PROTEIN, 17-KD, GRP17|OIG37, MOUSE, HOMOLOG OF | Locus: | 9q22.1-q22.2 in Homo sapiens |
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| General Comment | NCBI Summary: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. | ||||
| General function | Intracellular signaling cascade, Cell cycle regulation | ||||
| Comment | |||||
| Cellular localization | Cytoplasmic | ||||
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| Ovarian function | |||||
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| Expression regulated by | |||||
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| Ovarian localization | Oocyte | ||||
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| Follicle stages | Primordial | ||||
| Comment | Arraztoa JA, et al 2005 reported the identification of genes expressed in primate primordial oocytes. | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
| Links |
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| created: | June 21, 2006, 10:26 a.m. | by: |
alex email:
home page: |
| last update: | July 14, 2006, 4:36 p.m. | by: | hsueh email: |
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