| H2a Histone Family, Member Y | OKDB#: 3137 |
| Symbols: | H2AFY | Species: | human | ||
| Synonyms: | H2A.y, H2A/y, H2AFJ, mH2A1, H2AF12M, MACROH2A1.1, macroH2A1.2,MACRO H2A|MACRO H2A1|MH2A1 | Locus: | 5q31.3-q32 in Homo sapiens |
|
For retrieval of Nucleotide and Amino Acid sequences please go to:
OMIM
Entrez Gene
Mammalian Reproductive Genetics Endometrium Database Resource Orthologous Genes UCSC Genome Browser GEO Profiles new! Amazonia (transcriptome data) new! R-L INTERACTIONS MGI |
| General Comment | NCBI Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. | ||||
| General function | Cell cycle regulation | ||||
| Comment | |||||
| Cellular localization | Nuclear | ||||
| Comment | |||||
| Ovarian function | |||||
| Comment | |||||
| Expression regulated by | |||||
| Comment | |||||
| Ovarian localization | Oocyte | ||||
| Comment | |||||
| Follicle stages | Primordial | ||||
| Comment | Arraztoa JA, et al 2005 reported the identification of genes expressed in primate primordial oocytes. | ||||
| Phenotypes | |||||
| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
| Links |
|
| created: | June 21, 2006, 10:40 a.m. | by: |
alex email:
home page: |
| last update: | June 27, 2006, 3:48 p.m. | by: | hsueh email: |
Click here to return to gene search form