| Phosphatidylinositol-4-phosphate 5-kinase, Type Ii, Alpha | OKDB#: 3163 |
| Symbols: | PIP5K2A | Species: | human | ||
| Synonyms: | PIPK, PIP5KII-alpha,PHOSPHATIDYLINOSITOL-5-PHOSPHATE 4-KINASE, ALPHA, PI5P4KA | Locus: | 10p12.2 in Homo sapiens |
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| General Comment | NCBI Summary: Phosphatidylinositol-4,5-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-4-phosphate 5-kinase family. | ||||
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| Follicle stages | Primordial | ||||
| Comment | Arraztoa JA, et al 2005 reported the identification of genes expressed in primate primordial oocytes. | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | June 21, 2006, 11:17 a.m. | by: |
alex email:
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| last update: | June 21, 2006, 11:17 a.m. | by: | alex email: |
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