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Ovarian Kaleidoscope Database (OKdb)

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cellular repressor of E1A-stimulated genes 1 OKDB#: 3177
 Symbols: CREG1 Species: human
 Synonyms: CREG,  Locus: 1q24 in Homo sapiens


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General Comment NCBI Summary: The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.
General function Transcription factor
Comment
Cellular localization
Comment
Ovarian function
Comment
Expression regulated by
Comment
Ovarian localization
Comment
Follicle stages Primordial
Comment Arraztoa JA, et al 2005 reported the identification of genes expressed in primate primordial oocytes.
Phenotypes
Mutations 0 mutations
Genomic Region show genomic region
Phenotypes and GWAS show phenotypes and GWAS
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created: June 21, 2006, 11:41 a.m. by: alex   email:
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last update: June 21, 2006, 1:25 p.m. by: alex    email:



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