| mitochondrial ribosomal protein S5 | OKDB#: 3194 |
| Symbols: | MRPS5 | Species: | human | ||
| Synonyms: | MRP-S5, | Locus: | 2p11.2-q11.2 in Homo sapiens |
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Entrez Gene
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| General Comment | NCBI Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S5P family. Pseudogenes corresponding to this gene are found on chromosomes 4q, 5q, and 18q. | |||
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| Follicle stages | Primordial | |||
| Comment | Arraztoa JA, et al 2005 reported the identification of genes expressed in primate primordial oocytes. | |||
| Phenotypes | ||||
| Mutations | 0 mutations | |||
| Genomic Region | show genomic region | |||
| Phenotypes and GWAS | show phenotypes and GWAS | |||
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| created: | June 21, 2006, 12:54 p.m. | by: |
alex email:
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| last update: | June 21, 2006, 12:54 p.m. | by: | alex email: |
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