| Potassium Channel, Inwardly Rectifying, Subfamily J, Member 6 | OKDB#: 3229 |
| Symbols: | KCNJ6 | Species: | human | ||
| Synonyms: | BIR1, GIRK2, KATP2, KCNJ7, KIR3.2, hiGIRK2, MGC126596,GIRK2|POTASSIUM CHANNEL, INWARDLY RECTIFYING, SUBFAMILY J, MEMBER 7, FORMERLY, KCNJ7, FORMERLY | Locus: | 21q22.1 in Homo sapiens |
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| General Comment | NCBI Summary: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. | ||||
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| Ovarian function | Oogenesis, Oocyte maturation | ||||
| Comment | Gene whose expression is detected by cDNA array hybridization: oncogenes, tumor suppressors, cell cycle regulators Rozenn Dalbis-Tran and Pascal Mermilloda | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | June 22, 2006, 11:14 a.m. | by: |
alex email:
home page: |
| last update: | July 25, 2006, 2:54 p.m. | by: | Alex email: |
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