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Galanin Receptor 1 OKDB#: 3283
 Symbols: GALR1 Species: human
 Synonyms: GALNR, GALNR1,GALNR, GALNR1|GALANIN RECEPTOR 1, BRAIN  Locus: 18q23 in Homo sapiens
HPMR


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General Comment NCBI Summary: The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.
General function Receptor
Comment
Cellular localization Plasma membrane
Comment
Ovarian function Oogenesis, Oocyte maturation
Comment Gene whose expression is detected by cDNA array hybridization: transcription factors, cell signaling and extracellular communication Rozenn Dalbis-Tran and Pascal Mermilloda
Expression regulated by
Comment
Ovarian localization
Comment
Follicle stages
Comment
Phenotypes
Mutations 0 mutations
Genomic Region show genomic region
Phenotypes and GWAS show phenotypes and GWAS
Links
OMIM (Online Mendelian Inheritance in Man: an excellent source of general gene description and genetic information.)
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created: June 22, 2006, 2:59 p.m. by: alex   email:
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last update: July 26, 2006, 1:12 p.m. by: Alex    email:



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