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HPMR

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Nonmetastatic Cells 2, Protein Expressed In OKDB#: 3387
 Symbols: NME2 Species: human
 Synonyms: puf, NDPKB, NM23B, NM23-H2, MGC111212,METASTASIS INHIBITION FACTOR NM23B|NONMETASTATIC PROTEIN 23B, NM23B|NONMETASTATIC PROTEIN 23, HOMOLOG 2, NM23H2|NUCLEOSIDE DIPHOSPHATE KINASE-B, NDPKB  Locus: 17q21.3 in Homo sapiens


For retrieval of Nucleotide and Amino Acid sequences please go to: OMIM Entrez Gene
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General Comment NCBI Summary: Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. Co-transcription of this gene and the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) which encode a fusion protein comprised of sequence sharing identity with each individual gene product.
General function Enzyme, Transferase, Nucleic acid binding, DNA binding, Transcription factor
Comment
Cellular localization Nuclear
Comment
Ovarian function Oogenesis, Oocyte maturation
Comment Gene whose relative transcript level reproducibly increases during IVM Rozenn Dalbi?Tran and Pascal Mermilloda
Expression regulated by
Comment
Ovarian localization
Comment
Follicle stages
Comment
Phenotypes
Mutations 0 mutations
Genomic Region show genomic region
Phenotypes and GWAS show phenotypes and GWAS
Links
OMIM (Online Mendelian Inheritance in Man: an excellent source of general gene description and genetic information.)
OMIM \ Animal Model
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created: July 19, 2006, 11:07 a.m. by: Alex   email:
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last update: July 25, 2006, 11:58 a.m. by: Alex    email:



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