| squamous cell carcinoma antigen recognised by T cells 3 | OKDB#: 3631 |
| Symbols: | SART3 | Species: | human | ||
| Synonyms: | TIP110, KIAA0156, MGC138188, p110(nrb), RP11-13G14, | Locus: | 12q24.1 in Homo sapiens |
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Entrez Gene
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| General Comment | NCBI Summary: The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. | |||
| General function | ||||
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| Cellular localization | Nuclear | |||
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| Ovarian localization | Oocyte | |||
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| Phenotypes | ||||
| Mutations | 0 mutations | |||
| Genomic Region | show genomic region | |||
| Phenotypes and GWAS | show phenotypes and GWAS | |||
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| created: | Oct. 30, 2006, 4:44 p.m. | by: |
amazinmazin email:
home page: |
| last update: | Oct. 30, 2006, 4:44 p.m. | by: | amazinmazin email: |
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