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Ovarian Kaleidoscope Database (OKdb)

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HPMR

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176557

Destrin OKDB#: 3803
 Symbols: DSTN Species: human
 Synonyms: ADF, ACTDP, bA462D18.2,ACTIN DEPOLYMERIZING FACTOR, ADF  Locus: 20p12.1 in Homo sapiens


For retrieval of Nucleotide and Amino Acid sequences please go to: OMIM Entrez Gene
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R-L INTERACTIONS   MGI

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link to BioGPS
General Comment upstream of Hippo signaling

NCBI Summary: The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene.
General function Cytoskeleton
Comment
Cellular localization
Comment
Ovarian function Preantral follicle growth
Comment
Expression regulated by
Comment
Ovarian localization Oocyte, Granulosa
Comment
Follicle stages
Comment
Phenotypes
Mutations 0 mutations
Genomic Region show genomic region
Phenotypes and GWAS show phenotypes and GWAS
Links
OMIM (Online Mendelian Inheritance in Man: an excellent source of general gene description and genetic information.)
OMIM \ Animal Model
KEGG Pathways
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created: July 21, 2008, 5:28 p.m. by: hsuehlab   email:
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last update: None by: system    email:



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