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HPMR

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Kringle Domain-containing Transmembrane Protein 1 OKDB#: 3966
 Symbols: KREMEN1 Species: human
 Synonyms: KRM1, KREMEN, KREMEM1, FLJ31863,KRM1|KREMEN  Locus: 22q12.1 in Homo sapiens


For retrieval of Nucleotide and Amino Acid sequences please go to: OMIM Entrez Gene
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General Comment NCBI Summary: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq]
General function
Comment
Cellular localization
Comment
Ovarian function
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Expression regulated by
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Ovarian localization
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Follicle stages
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Phenotypes
Mutations 0 mutations
Genomic Region show genomic region
Phenotypes and GWAS show phenotypes and GWAS
Links
OMIM (Online Mendelian Inheritance in Man: an excellent source of general gene description and genetic information.)
OMIM \ Animal Model
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created: Feb. 2, 2009, 4:43 p.m. by: hsueh   email:
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last update: Feb. 2, 2009, 4:43 p.m. by: hsueh    email:



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