| Kringle Domain-containing Transmembrane Protein 1 | OKDB#: 3966 |
| Symbols: | KREMEN1 | Species: | human | ||
| Synonyms: | KRM1, KREMEN, KREMEM1, FLJ31863,KRM1|KREMEN | Locus: | 22q12.1 in Homo sapiens |
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Entrez Gene
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| General Comment | NCBI Summary: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq] | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | Feb. 2, 2009, 4:43 p.m. | by: |
hsueh email:
home page: |
| last update: | Feb. 2, 2009, 4:43 p.m. | by: | hsueh email: |
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