| Ornithine Decarboxylase Antizyme 1 | OKDB#: 4027 |
| Symbols: | OAZ1 | Species: | human | ||
| Synonyms: | AZI, OAZ, MGC138338,OAZ|ANTIZYME 1 | Locus: | 19p13.3 in Homo sapiens |
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| General Comment | NCBI Summary: Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase and accelerates its degradation. [provided by RefSeq] | ||||
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| Ovarian localization | Oocyte | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | March 4, 2009, 4:47 p.m. | by: |
hsueh email:
home page: |
| last update: | March 4, 2009, 4:48 p.m. | by: | hsueh email: |
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