| E4f Transcription Factor 1 | OKDB#: 4077 |
| Symbols: | E4F1 | Species: | human | ||
| Synonyms: | E4F, MGC99614,TRANSCRIPTION FACTOR E4F, E4F|p120 E4F | Locus: | 16p13.3 in Homo sapiens |
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| General Comment | NCBI Summary: The zinc finger protein encoded by this gene is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. A 50-kDa amino-terminal product is generated from the full-length protein through proteolytic cleavage. The protein is differentially regulated by E1A-induced phosphorylation. The full-length gene product represses transcription from the E4 promoter in the absence of E1A, while the 50-kDa form acts as a transcriptional activator in its presence. [provided by RefSeq] | ||||
| General function | DNA binding, Transcription factor | ||||
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| Cellular localization | Nuclear | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | April 16, 2009, 10:19 a.m. | by: |
hsueh email:
home page: |
| last update: | April 16, 2009, 10:20 a.m. | by: | hsueh email: |
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