| Interleukin 28b | OKDB#: 4229 |
| Symbols: | IL28B | Species: | human | ||
| Synonyms: | IFNL3, IL28C, IL-28B,INTERFERON, LAMBDA-3, IFNL3 | Locus: | 19q13.13 in Homo sapiens |
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| General Comment | NCBI Summary: This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq] | ||||
| General function | Ligand, Cytokine | ||||
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| Cellular localization | Secreted | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | Feb. 22, 2010, 11:21 a.m. | by: |
hsueh email:
home page: |
| last update: | Feb. 22, 2010, 11:21 a.m. | by: | hsueh email: |
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