| MAX dimerization protein 4 | OKDB#: 4265 |
| Symbols: | MXD4 | Species: | human | ||
| Synonyms: | MAD4, MST149, MSTP149, bHLHc12, | Locus: | 4p16.3 in Homo sapiens |
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| General Comment | NCBI Summary: This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq] | |||
| General function | Nucleic acid binding, DNA binding, Transcription factor | |||
| Comment | ||||
| Cellular localization | Nuclear | |||
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| Ovarian function | ||||
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| Expression regulated by | ||||
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| Ovarian localization | Oocyte | |||
| Comment | oxyz | |||
| Follicle stages | ||||
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| Phenotypes | ||||
| Mutations | 0 mutations | |||
| Genomic Region | show genomic region | |||
| Phenotypes and GWAS | show phenotypes and GWAS | |||
| Links |
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| created: | April 1, 2010, 10:16 a.m. | by: |
hsueh email:
home page: |
| last update: | April 1, 2010, 10:18 a.m. | by: | hsueh email: |
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