| Solute Carrier Family 25, Member 11 | OKDB#: 443 |
| Symbols: | SLC25A11 | Species: | rat | ||
| Synonyms: | SOLUTE CARRIER FAMILY 20, MEMBER 4, FORMERLY, SLC20A4, FORMERLY| OXOGLUTARATE CARRIER, OGC| OXOGLUTARATE/MALATE CARRIER| | Locus: | 17p13.3 in Homo sapiens |
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| General Comment |
Oxoglutarate carriers transport oxoglutarate across the inner membranes of mitochondria in exchange for malate. Oxoglutarate carriers belong to the mitochondrial carrier protein family, characterized by a tripartite structure made up of related sequences about 100 amino acids in length. The N- and C-terminal regions are exposed toward the cytosol. In addition, the oxoglutarate carrier has been shown to be a dimer by means of crosslinking studies. The bovine and human genes coding for the oxoglutarate carrier are split into eight and six exons, respectively, and five introns are found to the same position in both genes (Palmieri et al., 1993 ).
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| General function | Metabolism | ||||
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| Cellular localization | Mitochondrial | ||||
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| Ovarian function | |||||
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| Expression regulated by | |||||
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| Ovarian localization | |||||
| Comment | This gene was found in a rat ovarian cDNA library (Unigene) | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
| Links |
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| created: | Jan. 31, 2000, midnight | by: |
kmwasson email:
home page: |
| last update: | Aug. 3, 2001, 3:21 p.m. | by: | uschi email: |
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