| Calponin 1 | OKDB#: 445 |
| Symbols: | CNN1 | Species: | rat | ||
| Synonyms: | CALPONIN, BASIC, SMOOTH MUSCLE| CALPONIN H1, MOUSE, HOMOLOG OF| SMOOTH MUSCLE-CELL CALPONIN, SMCC| | Locus: | 19p13.2 in Homo sapiens |
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| General Comment |
Calponin is a basic 34-kD protein first isolated from chicken gizzard and bovine aorta. It is specifically expressed in smooth muscle and binds calmodulin, actin, and tropomyosin. It is able to inhibit the ATPase activity of myosin and is thought to play a role in smooth muscle contraction. [ Strasser et al. (1993) $8370452 ] isolated 2 similar calponins (h1 and h2) from both mouse and pig. These are the products of separate loci.
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| General function | |||||
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| Cellular localization | Cytoplasmic | ||||
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| Ovarian function | |||||
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| Ovarian localization | |||||
| Comment | This gene was found in a rat ovarian cDNA library (Unigene) | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
| Links |
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| created: | Jan. 31, 2000, midnight | by: |
Hsueh email:
home page: |
| last update: | Aug. 13, 2001, 11:51 a.m. | by: | Hsueh email: |
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