| thyroid hormone receptor interactor 6 | OKDB#: 4594 |
| Symbols: | TRIP6 | Species: | human | ||
| Synonyms: | OIP1, OIP-1, ZRP-1, TRIP-6, TRIP6i2, | Locus: | 7q22 in Homo sapiens |
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| General Comment |
Interacts with Zyxin, upstream of Hippo signaling
NCBI Summary: This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] |
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| General function | Intracellular signaling cascade | ||||
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| Cellular localization | Plasma membrane | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
| Links |
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| created: | Jan. 1, 2012, 4:27 p.m. | by: |
hsueh email:
home page: |
| last update: | April 30, 2012, 2:55 p.m. | by: | hsueh email: |
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