| forkhead box P1 | OKDB#: 4791 |
| Symbols: | FOXP1 | Species: | human | ||
| Synonyms: | QRF1, 12CC4, hFKH1B, HSPC215,QPC, QCR8, QP-C, UQCR7, | Locus: | 3p14.1 in Homo sapiens |
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| General Comment | NCBI Summary: This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] | ||||
| General function | Nucleic acid binding, DNA binding, Transcription factor | ||||
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| Cellular localization | Nuclear | ||||
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| Ovarian function | |||||
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| Expression regulated by | LH | ||||
| Comment | Increased after the preovulatory LH surge | ||||
| Ovarian localization | |||||
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| Follicle stages | |||||
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| Phenotypes | |||||
| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
| Links |
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| created: | Nov. 27, 2012, 9:01 a.m. | by: |
hsueh email:
home page: |
| last update: | Nov. 27, 2012, 9:04 a.m. | by: | hsueh email: |
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