| secretory leukocyte peptidase inhibitor | OKDB#: 5182 |
| Symbols: | SLPI | Species: | human | ||
| Synonyms: | ALP, MPI, ALK1, BLPI, HUSI, WAP4, WFDC4, HUSI-I | Locus: | 20q12 in Homo sapiens |
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OMIM
Entrez Gene
Mammalian Reproductive Genetics Endometrium Database Resource Orthologous Genes UCSC Genome Browser GEO Profiles new! Amazonia (transcriptome data) new! R-L INTERACTIONS MGI |
| General Comment | NCBI Summary: This gene encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes. This antimicrobial protein has antibacterial, antifungal and antiviral activity. [provided by RefSeq, Nov 2014] | ||||
| General function | Extracellular binding protein | ||||
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| Cellular localization | Secreted | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | May 3, 2015, 4:25 p.m. | by: |
system email:
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| last update: | May 3, 2015, 4:25 p.m. | by: | hsueh email: |
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