| dedicator of cytokinesis 1 | OKDB#: 5213 |
| Symbols: | DOCK1 | Species: | human | ||
| Synonyms: | ced5, DOCK180 | Locus: | 10q26.13-q26.3 in Homo sapiens |
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| General Comment | NCBI Summary: This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] | ||||
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| Ovarian localization | Oocyte, Granulosa | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | June 19, 2015, 12:23 p.m. | by: |
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| last update: | June 19, 2015, 12:26 p.m. | by: | hsueh email: |
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