| cytochrome P450 family 3 subfamily A member 7 | OKDB#: 5352 |
| Symbols: | CYP3A7 | Species: | human | ||
| Synonyms: | CP37, CYPIIIA7, P450-HFLA, P-450111A7, P-450(HFL33) | Locus: | 7q22.1 in Homo sapiens |
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| General Comment | NCBI Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3A51P pseudogene and is represented by GeneID:100861540. [provided by RefSeq, Jan 2015] | ||||
| General function | Enzyme | ||||
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| Cellular localization | Cytoplasmic | ||||
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| Ovarian function | Steroid metabolism | ||||
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| Ovarian localization | Granulosa | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | Feb. 16, 2016, 5:38 a.m. | by: |
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| last update: | Feb. 16, 2016, 9:24 a.m. | by: | hsueh email: |
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