N-acetyltransferase 2 | OKDB#: 5420 |
Symbols: | NAT2 | Species: | human | ||
Synonyms: | AAC2, PNAT, NAT-2 | Locus: | 8p22 in Homo sapiens |
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Entrez Gene
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General Comment | NCBI Summary: This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq, Jul 2008] | ||||
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Mutations | 0 mutations | ||||
Genomic Region | show genomic region | ||||
Phenotypes and GWAS | show phenotypes and GWAS | ||||
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created: | Nov. 27, 2016, 11:46 a.m. | by: |
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last update: | Nov. 27, 2016, 11:46 a.m. | by: | system email: |
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