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Ovarian Kaleidoscope Database (OKdb)

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N-acetyltransferase 2 OKDB#: 5420
 Symbols: NAT2 Species: human
 Synonyms: AAC2, PNAT, NAT-2  Locus: 8p22 in Homo sapiens


For retrieval of Nucleotide and Amino Acid sequences please go to: OMIM Entrez Gene
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General Comment NCBI Summary: This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq, Jul 2008]
General function
Comment
Cellular localization
Comment
Ovarian function
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Expression regulated by
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Ovarian localization
Comment
Follicle stages
Comment
Phenotypes
Mutations 0 mutations
Genomic Region show genomic region
Phenotypes and GWAS show phenotypes and GWAS
Links
OMIM (Online Mendelian Inheritance in Man: an excellent source of general gene description and genetic information.)
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created: Nov. 27, 2016, 11:46 a.m. by: system   email:
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last update: Nov. 27, 2016, 11:46 a.m. by: system    email:



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