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Ovarian Kaleidoscope Database (OKdb)

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NIMA related kinase 4 OKDB#: 5541
 Symbols: NEK4 Species: human
 Synonyms: NRK2, STK2, pp12301  Locus: 3p21.1 in Homo sapiens


For retrieval of Nucleotide and Amino Acid sequences please go to: OMIM Entrez Gene
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link to BioGPS
General Comment NCBI Summary: The protein encoded by this gene is a serine/threonine protein kinase required for normal entry into replicative senescence. The encoded protein also is involved in cell cycle arrest in response to double-stranded DNA damage. Finally, this protein plays a role in maintaining cilium integrity, and defects in this gene have been associated with ciliopathies. [provided by RefSeq, Jan 2017]
General function Cell death/survival, Cell cycle regulation, Enzyme
Comment
Cellular localization
Comment
Ovarian function
Comment
Expression regulated by
Comment
Ovarian localization Cumulus
Comment
Follicle stages
Comment
Phenotypes
Mutations 0 mutations
Genomic Region show genomic region
Phenotypes and GWAS show phenotypes and GWAS
Links
OMIM (Online Mendelian Inheritance in Man: an excellent source of general gene description and genetic information.)
OMIM \ Animal Model
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created: Feb. 16, 2018, 10:51 a.m. by: system   email:
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last update: Feb. 16, 2018, 10:52 a.m. by: hsueh    email:



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