| Kruppel like factor 12 | OKDB#: 5638 |
| Symbols: | KLF12 | Species: | human | ||
| Synonyms: | AP2REP, AP-2rep, HSPC122 | Locus: | 13q22.1 in Homo sapiens |
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| General Comment | NCBI Summary: Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | ||||
| General function | Transcription factor | ||||
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| Cellular localization | Nuclear | ||||
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| Ovarian localization | Oocyte | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | July 30, 2019, 2:03 p.m. | by: |
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| last update: | July 30, 2019, 2:04 p.m. | by: | hsueh email: |
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