| gonadotropin releasing hormone receptor 2 (pseudogene) | OKDB#: 5713 |
| Symbols: | GNRHR2 | Species: | human | ||
| Synonyms: | GnRH-II-R | Locus: | 1q21.1 in Homo sapiens |
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| General Comment | NCBI Summary: In non-hominoid primates and non-mammalian vertebrates, the gonadotropin releasing hormone 2 receptor gene (GnRHR2) encodes a seven-transmembrane G-protein coupled receptor. However, in human, the corresponding reading frame contains a premature stop codon, which has been suggested to encode a selenocysteine residue, but there is no solid evidence for selenocysteine incorporation (PMID: 12538601). It appears that the human GnRHR2 transcription occurs but the gene does not likely produce a functional multi-transmembrane protein. A non-transcribed pseudogene of GnRHR2 is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2013] | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | Feb. 20, 2020, 1:43 p.m. | by: |
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| last update: | Feb. 20, 2020, 1:43 p.m. | by: | hsueh email: |
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