| tousled like kinase 2 | OKDB#: 5741 |
| Symbols: | TLK2 | Species: | human | ||
| Synonyms: | HsHPK, MRD57, PKU-ALPHA | Locus: | 17q23.2 in Homo sapiens |
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| General Comment | NCBI Summary: This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] | ||||
| General function | DNA repair | ||||
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| Cellular localization | Nuclear | ||||
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| Ovarian localization | Oocyte | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | March 22, 2020, 11:19 a.m. | by: |
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| last update: | March 22, 2020, 11:20 a.m. | by: | hsueh email: |
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