| glucokinase regulator | OKDB#: 5819 |
| Symbols: | GCKR | Species: | human | ||
| Synonyms: | GKRP, FGQTL5 | Locus: | 2p23.3 in Homo sapiens |
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| General Comment | NCBI Summary: This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008] | ||||
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| Cellular localization | Cytoplasmic | ||||
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| Ovarian localization | Oocyte | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | July 1, 2020, 2:04 p.m. | by: |
system email:
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| last update: | July 1, 2020, 2:06 p.m. | by: | hsueh email: |
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