glycosylphosphatidylinositol specific phospholipase D1 | OKDB#: 5825 |
Symbols: | GPLD1 | Species: | human | ||
Synonyms: | PLD, GPIPLD, PIGPLD, GPIPLDM, PIGPLD1 | Locus: | 6p22.3 in Homo sapiens |
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General Comment | NCBI Summary: Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. [provided by RefSeq, Jul 2008] | ||||
General function | Enzyme | ||||
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Cellular localization | Secreted, Plasma membrane | ||||
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Ovarian function | |||||
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Ovarian localization | Oocyte, Granulosa | ||||
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Mutations | 0 mutations | ||||
Genomic Region | show genomic region | ||||
Phenotypes and GWAS | show phenotypes and GWAS | ||||
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created: | July 15, 2020, 3:02 p.m. | by: |
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last update: | July 15, 2020, 3:04 p.m. | by: | hsueh email: |
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