| ATP binding cassette subfamily C member 4 | OKDB#: 5912 |
| Symbols: | ABCC4 | Species: | human | ||
| Synonyms: | MRP4, MOATB, MOAT-B | Locus: | 13q32.1 in Homo sapiens |
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| General Comment | NCBI Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014] | ||||
| General function | Channel/transport protein | ||||
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| Cellular localization | Plasma membrane | ||||
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| Ovarian localization | Oocyte | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | Feb. 17, 2021, 3:59 a.m. | by: |
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| last update: | Feb. 17, 2021, 4 a.m. | by: | hsueh email: |
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