| interferon gamma inducible protein 16 | OKDB#: 5913 |
| Symbols: | IFI16 | Species: | human | ||
| Synonyms: | PYHIN2, IFNGIP1 | Locus: | 1q23.1 in Homo sapiens |
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For retrieval of Nucleotide and Amino Acid sequences please go to:
OMIM
Entrez Gene
Mammalian Reproductive Genetics Endometrium Database Resource Orthologous Genes UCSC Genome Browser GEO Profiles new! Amazonia (transcriptome data) new! R-L INTERACTIONS MGI |
| General Comment |
This gene is involved in pyroptosis
NCBI Summary: This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011] |
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| General function | Intracellular signaling cascade | ||||
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| Cellular localization | Cytoplasmic | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | Feb. 23, 2021, 8:02 p.m. | by: |
system email:
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| last update: | Feb. 23, 2021, 8:03 p.m. | by: | hsueh email: |
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