| ATP-ase, H+ Transporting, Lysosomal, Subunit F | OKDB#: 596 |
| Symbols: | ATP6F | Species: | rat | ||
| Synonyms: | VACUOLAR PROTON PUMP, 21-KD SUBUNIT| | Locus: | 1p32.3 in Homo sapiens |
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| General Comment |
Vacuolar-type H(+)-ATPase (V-ATPase) is a multisubunit enzyme responsible for acidification of eukaryotic intracellular
organelles. V-ATPase-dependent organelle acidification is essential for intracellular processes such as protein sorting,
zymogen activation, and receptor-mediated endocytosis. The V-ATPase is composed of peripheral (V1) and integral (V0)
membrane sectors. Proteolipids are major components of the V0 sector.
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| General function | Enzyme, Oxidoreductase | ||||
| Comment | |||||
| Cellular localization | Cytoplasmic | ||||
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| Ovarian function | Unknown | ||||
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| Expression regulated by | |||||
| Comment | |||||
| Ovarian localization | |||||
| Comment | This gene was found in a rat ovarian cDNA library (Unigene) | ||||
| Follicle stages | |||||
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| Phenotypes | |||||
| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
| Links |
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| created: | Jan. 31, 2000, midnight | by: |
uni email:
home page: |
| last update: | Aug. 14, 2001, 10:15 a.m. | by: | hsueh email: |
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